Table 4

Changes in adipokines during the weight loss period1
IFCR-L IFCR-F
Week 3 Week 10 Change2 Week 3 Week 10 Change2
Leptin (ng/ml) 36.5 ± 2.5 27.1 ± 3.1 3 −9.4 ± 1.6 37.6 ± 2.5 29.4 ± 2.4 3 −8.2 ± 1.7
IL-6 (pg/ml) 3.1 ± 0.3 2.5 ± 0.3 3 −0.6 ± 0.3 3.1 ± 0.4 3.3 ± 0.4 0.2 ± 0.4
TNF-alpha (pg/ml) 1.6 ± 0.3 1.2 ± 0.3 3 −0.4 ± 0.1 1.2 ± 0.3 1.1 ± 0.2 −0.1 ± 0.1
C-Reactive protein (mg/dl) 0.4 ± 0.1 0.4 ± 0.1 0 ± 0.1 0.6 ± 0.2 0.4 ± 0.1 −0.2 ± 0.2
8-isoprostane (pmol/mg) 1.8 ± 0.1 1.9 ± 0.1 0.1 ± 0.1 1.8 ± 0.1 1.9 ± 0.1 0.1 ± 0.1
IGF-1 (ng/ml) 67.7 ± 3.8 60.8 ± 4.2 3 −6.9 ± 2.3 69.6 ± 3.8 67.6 ± 5.4 −2.0 ± 4.9

1 Values reported as mean ± SEM. IFCR-L: Intermittent fasting calorie restriction-liquid diet (n = 28); IFCR-F: Intermittent fasting calorie restriction-food based diet (n = 26). IL-6: Interleukin-6, TNF-alpha: Tumor necrosis factor-alpha, IGF-1: Insulin-like growth factor-1.

2 Change expressed as the difference between week 3 and week 10 absolute values.

3 Week 3 values significantly (P < 0.05) different from week 10 values within group (Repeated-measures ANOVA).

Kroeger et al.

Kroeger et al. Nutrition & Metabolism 2012 9:98   doi:10.1186/1743-7075-9-98

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