Table 3 |
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|
Markers of colonic fermentation, according to diet, after 6 and 18 weeks. |
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|
6 weeks |
18 weeks |
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|
|
|
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|
control |
HCF |
HP |
MIX |
p value |
control |
HCF |
HP |
MIX |
p value1 |
|
|
Fecal SCFA (mM) |
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|
Acetate (C2) |
34.4 ± 3.3 |
42.2 ± 6.1 |
37.4 ± 2.8 |
41.7 ± 5.4 |
0.75 |
37.2 ± 2.6 |
44.1 ± 5.7 |
40.4 ± 3.9 |
39.8 ± 5.3 |
0.79 |
|
Propionate (C3) |
12.8 ± 1.8 |
13.1 ± 1.7 |
15.0 ± 1.6 |
15.4 ± 1.6 |
0.28 |
14.1 ± 1.4 |
16.5 ± 2.2 |
17.4 ± 2.3 |
13.7 ± 1.2 |
0.77 |
|
Butyrate (C4) |
11.3 ± 2.1 |
15.1 ± 2.8 |
15.6 ± 1.7 |
14.8 ± 2.7 |
0.41 |
13.3 ± 1.8 |
13.8 ± 2.0 |
12.9 ± 1.4 |
12.4 ± 1.7 |
0.98 |
|
Valerate (C5) |
2.2 ± 0.3 |
1.9 ± 0.3 |
3.1 ± 0.3 |
2.4 ± 0.3 |
0.037 |
2.9 ± 0.3 |
2.4 ± 0.3 |
3.1 ± 0.4 |
2.6 ± 0.3 |
0.48 |
|
Sum SCFA2 |
63.7 ± 6.4 |
74.8 ± 9.5 |
75.6 ± 5.9 |
77.6 ± 9.0 |
0.42 |
71.6 ± 5.6 |
80.4 ± 9.7 |
78.2 ± 7.2 |
72.1 ± 7.3 |
0.90 |
|
Fecal dry mass (FDM, %) |
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|
FDM (%) |
25.4 ± 2.1 |
34.3 ± 2.7 |
28.2 ± 1.9 |
28.3 ± 1.8 |
0.08 |
27.8 ± 1.4 |
30.4 ± 2.7 |
27.0 ± 1.7 |
30.1 ± 2.3 |
0.35 |
|
|
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|
All values are mean ± SEM. Baseline values are shown in Table 1. HCF, diet high in cereal fiber; HP, diet high in protein; MIX, diet moderately high in both cereal and protein. 1P values refer to the respective treatment × time interaction in the full model. 2Sum SCFA includes the measurement of fecal iso-acids |
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|
Weickert et al. Nutrition & Metabolism 2011 8:90 doi:10.1186/1743-7075-8-90 |
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