Table 1

Effect of GvEx on glomeruli in db/db mice

Glomeruli


Group

Number of thickened matrix 1)


Control (n = 10)

11.3 ± 2.7

GvEx (n = 9)

7.2 ± 2.6 **


Six-week-old db/db (C57BL/KsJ) mice were equally divided into 2 groups according to body weight. All animals were permitted water or GvEx solution (250 mg/kg bw/day) mixed in tap water and diet (MF commercial diet, Oriental Yeast Co., Ltd., Tokyo, Japan) ad libitum. The study period was 7 weeks [15].

1) Number of glomeruli per specimen with moderate and marked changes.

Values are expressed as mean ± SD. **: p < 0.01 (Student's t-test).

Deguchi and Miyazaki Nutrition & Metabolism 2010 7:9   doi:10.1186/1743-7075-7-9

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