Table 2 |
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|
Plasma bile acid levels and energy expenditure in patient groups with liver cirrhosis |
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|
cirrhosis (all) (n = 46) |
cholestatic subgroup (n = 14) |
non-cholestatic subgroup (n = 14) |
normal value |
|
|
|
||||
|
Total BA (μM) |
31.2 ± 3.3 |
40.5 ± 3.4 |
11.9 ± 1.5 |
< 10 |
|
CA (μM) |
10.3 ± 2.2 |
13.2 ± 0.7 |
4.2 ± 0.7# |
<1.0 |
|
CDCA (μM) |
13.7 ± 2.9 |
16.1 ± 4.3 |
6.7 ± 1.7# |
<3.0 |
|
DCA (μM) |
3.02 ± 1.48 |
5.81 ± 2.99 |
0.60 ± 0.16# |
<1.0 |
|
REE (kcal/d/1.73 m2) |
1716 ± 33 |
1676 ± 64 |
1650 ± 58 |
|
|
REE (kcal/d/kg FFM) |
36.9 ± 0.8 |
38.5 ± 1.9 |
37.9 ± 1.3 |
|
|
REE (% increase) |
18 ± 2 |
19 ± 4 |
18 ± 3 |
|
|
|
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|
Data are given as means ± SEM. BA, bile acids; CA, cholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; REE, resting energy expenditure; FFM, fat free mass. The percent increase in REE is the measured value related to the value predicted by use of the Harris-Benedict formula as described in the text. # Significantly different from the cholestatic subgroup as determined by Mann-Whitney U-test, at least P < 0.05. |
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|
Brufau et al. Nutrition & Metabolism 2010 7:73 doi:10.1186/1743-7075-7-73 |
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