Nutrition & Metabolism

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Open Access Research

Increased hypolipidemic benefits of cis-9, trans-11 conjugated linoleic acid in combination with trans-11 vaccenic acid in a rodent model of the metabolic syndrome, the JCR:LA-cp rat

M Miriam Jacome-Sosa1,2,3, Jing Lu1,2,3, Ye Wang1,2,3, Megan R Ruth2,3, David C Wright2,3, Martin J Reaney4, Jianheng Shen4, Catherine J Field2,3, Donna F Vine1,2,3 and Spencer D Proctor1,2,3*

Author Affiliations

1 Metabolic and Cardiovascular Diseases Laboratory, University of Alberta, Edmonton, AB, T6G 2P5, Canada

2 Alberta Institute for Human Nutrition, University of Alberta, Edmonton, AB, T6G 2P5, Canada

3 Alberta Diabetes Institute, University of Alberta, Edmonton, AB, T6G 2P5, Canada

4 Department of Applied Microbiology and Food Science, University of Saskatchewan, Saskatoon, SK, S7N 5A8, Canada

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Nutrition & Metabolism 2010, 7:60 doi:10.1186/1743-7075-7-60

Published: 16 July 2010

Additional files

Additional file 1:

Changes in body weight throughout the study and schematic representation of the experimental design. Rats (n = 8) were fed a standard chow diet prior to the study (from 3-8 wk of age). Then, control and experimental diets were provided for 16 wk. An oral fat challenge test (OFC) and a meal tolerance test (MTT) were conducted on different rats (n = 4 in each test).

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