Table 2 |
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|
Change from baseline in homodynamic, arterial stiffness and metabolic variables in each group |
||||||
|
Variables |
Patients received antioxidants |
Patients received placebo |
||||
|
|
||||||
|
baseline |
6 month |
p-value |
baseline |
6 month |
p-value |
|
|
|
||||||
|
Systolic BP (mm/Hg) |
145.2 ± 25.4 |
136.1 ± 22.3 |
0.001 |
138.0 ± 20.8 |
135.0 ± 21.6 |
0.257 |
|
|
||||||
|
Diastolic BP (mm/Hg) |
78.4 ± 11.7 |
75.0 ± 12.3 |
0.034 |
75.9 ± 7.8 |
75.0 ± 10.3 |
0.493 |
|
|
||||||
|
LAEI(ml/mm Hg × 10) |
11.0 ± 4.4 |
12.7 ± 4.7 |
0.006 |
12.9 ± 6.2 |
11.3 ± 4.3 |
0.151 |
|
|
||||||
|
SAEI(ml/mm Hg × 100) |
3.3 ± 1.9 |
4.7 ± 2.7 |
0.0001 |
3.6 ± 1.6 |
3.7 ± 1.9 |
0.732 |
|
|
||||||
|
SVR(dynes•sec/cm5) |
1817.0 ± 751.5 |
1617.3 ± 305.2 |
0.102 |
1594.9 ± 351.3 |
1638.7 ± 311.3 |
0.533 |
|
|
||||||
|
Glucose(mg/dl) |
127.0 ± 52 |
129 ± 62 |
0.535 |
118.9 ± 42 |
123.2 ± 55 |
0.496 |
|
|
||||||
|
HbA1C(%) |
7.08 ± 1.69 |
6.33 ± 2.3 |
0.022 |
6.82 ± 1.44 |
6.86 ± 1.66 |
0.767 |
|
|
||||||
|
Total Cholesterol(mg/dl) |
201.5 ± 53.1 |
180.7 ± 58.3 |
0.074 |
197.12 ± 50 |
186.80 ± 37.78 |
0.125 |
|
|
||||||
|
Triglycerides(mg/dl) |
189 ± 94 |
170.4 ± 72 |
0.058 |
124.5 ± 56.5 |
127.83 ± 46.7 |
0.645 |
|
|
||||||
|
HDL% |
22.1 ± 4 |
26.2 ± 10 |
0.022 |
26 ± 5.4 |
27.11 ± 5.5 |
0.212 |
|
|
||||||
|
LDL Cholesterol(mg/dl) |
116.8 ± 44.4 |
103.4 ± 47 |
0.13 |
117.91 ± 47.9 |
109.0 ± 33.1 |
0.135 |
|
|
||||||
|
hs-CRP(mg/dl) |
1.94 ± 3 |
0.62 ± 0.77 |
0.222 |
1.44 ± 1.59 |
0.95 ± 0.90 |
0.271 |
|
|
||||||
|
Renin (ng/ml/hr) |
1.79 ± 3.4 |
2.27 ± 2.6 |
0.494 |
1.36 ± 1.55 |
1.91 ± 1.87 |
0.149 |
|
|
||||||
|
Aldosterone(pg/ml) |
7.38 ± 5.6 |
8.2 ± 5.06 |
0.354 |
6.70 ± 4.5 |
7.00 ± 3.84 |
0.638 |
|
|
||||||
|
Homocysteine(μmol/l) |
9.24 ± 2.82 |
9.19 ± 2.83 |
0.911 |
8.75 ± 3.04 |
9.11 ± 3.3 |
0.139 |
|
|
||||||
|
Ur cathacholamines(mg/24 h) |
24.74 ± 21 |
28.5 ± 19 |
0.118 |
19.54 ± 12 |
22 ± 20 |
0.283 |
|
|
||||||
|
|
||||||
|
Shargorodsky et al. Nutrition & Metabolism 2010 7:55 doi:10.1186/1743-7075-7-55 |
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