Table 5 |
||||
|
mRNA levels of proinflammatory gene expression from PBMC with respect to tertiles (T)a of energy-adjusted fruit and vegetable consumption, fiber from fruit and vegetable consumption and dietary TAC (n = 120) |
||||
|
Proinflammatory gene expression (arbitrary units) |
Energy-adj. fruit and vegetable consumption |
P for trend |
||
|
|
||||
|
T1 (<384 g/d) |
T2 (384-660 g/d) |
T3 (>660 g/d) |
||
|
|
||||
|
ICAM1 |
2.03 ± 0.43 |
1.81 ± 0.40 |
1.75 ± 0.50 |
0.002 |
|
IL1R1 |
2.10 ± 0.58 |
1.95 ± 0.53 |
1.80 ± 0.56 |
0.003 |
|
IL6 |
2.02 ± 0.52 |
1.94 ± 0.61 |
1.75 ± 0.79 |
0.005 |
|
TNFα |
1.96 ± 0.53 |
1.81 ± 0.49 |
1.68 ± 0.65 |
0.025 |
|
NFκB1(p50) |
6.28 ± 4.81 |
5.08 ± 3.30 |
3.60 ± 1.90 |
0.004 |
|
RELA (p65) |
3.49 ± 2.70 |
2.48 ± 1.85 |
2.17 ± 2.10 |
0.055 |
|
|
||||
|
Energy adj. fiber from fruits and vegetables |
P for trend |
|||
|
|
||||
|
T1 (<6.0 g/d) |
T2 (6.0-19.5 g/d) |
T3 (>19.5 g/d) |
||
|
|
||||
|
ICAM1 |
1.94 ± 0.38 |
1.87 ± 0.47 |
1.77 ± 0.47 |
0.007 |
|
IL1R1 |
1.99 ± 0.54 |
1.95 ± 0.59 |
1.88 ± 0.57 |
0.263 |
|
IL6 |
2.0 ± 0.52 |
1.90 ± 0.74 |
1.81 ± 0.63 |
0.156 |
|
TNFα |
1.89 ± 0.49 |
1.81 ± 0.64 |
1.74 ± 0.55 |
0.012 |
|
NFκB1(p50) |
5.92 ± 2.36 |
5.30 ± 3.51 |
3.67 ± 2.53 |
0.011 |
|
RELA (p65) |
3.05 ± 2.36 |
2.94 ± 2.31 |
2.17 ± 1.62 |
0.104 |
|
|
||||
|
Energy-adjusted dietary TAC |
P for trend |
|||
|
|
||||
|
T1 (<5.3 mmol/d) |
T2 (5.3-11.8 mmol/d) |
T3 (>11.8 mmol/d) |
||
|
|
||||
|
ICAM1 |
1.91 ± 0.42 |
1.87 ± 0.47 |
1.79 ± 0.48 |
0.038 |
|
IL1R1 |
1.99 ± 0.57 |
1.95 ± 0.54 |
1.88 ± 0.59 |
0.020 |
|
IL6 |
1.97 ± 0.67 |
1.92 ± 0.65 |
1.85 ± 0.63 |
0.042 |
|
TNFα |
1.89 ± 0.60 |
1.81 ± 0.51 |
1.75 ± 0.59 |
0.031 |
|
NFκB1(p50) |
5.65 ± 4.51 |
5.21 ± 3.83 |
4.05 ± 2.17 |
0.035 |
|
RELA (p65) |
3.05 ± 2.53 |
2.85 ± 1.95 |
2.30 ± 1.85 |
0.088 |
|
|
||||
|
a Tertile 1, n = 39; Tertile 2, n = 42; Tertile 3, n = 39. P for trend from linear regression model, adjusting for gender, age, BMI, energy intake, physical activity, smoking, systolic blood pressure and non-esterified fatty acid concentration. TAC, total antioxidant capacity; ICAM1, intercellular adhesion molecule-1; IL1R1, interleukin-1 receptor-1; IL6, interleukin-6; NFκB1, nuclear factor-nuclear-kappa-B (p50); PBMC, peripheral blood mononuclear cells; RELA, nuclear factor-nuclear-kappa-B (p65); TNFα, tumor necrosis factor-alpha. |
||||
|
Hermsdorff et al. Nutrition & Metabolism 2010 7:42 doi:10.1186/1743-7075-7-42 |
||||
