Table 2

cAMP tissue/cell content in three main WAT sites of overweight male rats treated for 10 days with combined OE and B3A

organ/tissue

units

control

OE

B3A

OE+B3A

P-OE

P-B3A

P-int

inguinal subcutaneous WAT

amol/cell

1.91 ± 0.42

1.92 ± 0.30

2.37 ± 0.37

1.88 ± 0.59

NS

NS

NS

nmol

0.93 ± 0.11

0.73 ± 0.09

1.14 ± 0.22

0.97 ± 0.22

NS

NS

NS

epididymal WAT

amol/cell

3.74 ± 0.57

2.72 ± 0.20

5.92 ± 0.39

4.71 ± 0.36

0.0117

0.0000

NS

nmol

1.35 ± 0.17

1.09 ± 0.10

2.61 ± 0.31

2.06 ± 0.31

NS

0.0002

NS

retroperitoneal WAT

amol/cell

6.02 ± 0.42

4.53 ± 0.86

4.64 ± 0.20

3.83 ± 0.75

NS

NS

NS

nmol

2.52 ± 0.30

1.31 ± 0.26

1.75 ± 0.23

1.61 ± 0.27

0.0197

NS

NS

combined WAT

nmol

4.79 ± 0.43

3.49 ± 0.35

5.49 ± 0.46

4.66 ± 0.67

0.0427

0.0000

NS

The values are the mean ± sem of 6 different animals. Statistical significance of the diferences (2-way ANOVA): P-OE/PB3A represents the P values for OE/B3A inducing a significant effect on the given parameter; P-int indicates the significance of the interaction between both agonists. NS = p > 0.05.

Ferrer-Lorente et al. Nutrition & Metabolism 2010 7:15   doi:10.1186/1743-7075-7-15