Table 2 |
||
|
Important biological effects of CLA in human subjects. |
||
|
Treatment |
Effect |
Ref |
|
|
||
|
CLA with creatine |
CLA and creatine as adjuncts increased mictochondrial function by reducing sarcopenia and decreased oxidative stress in older adults |
[116] |
|
CLA with ω-3 fatty acids |
prevents increased abdominal fat and increases fat-free mass and adiponectin. |
[28] |
|
9-CLA |
No adverse effect on coronary vascular disease |
[126] |
|
9-CLA |
Modest anti-inflammatroy effect in allegic subjects |
[32] |
|
CLA with γ-oryzanol |
Reduced blood pressure and body fat. |
[127] |
|
9-and 10-CLA |
Enhanced fat oxidation and energy expenditure during sleep |
[50] |
|
10-CLA |
Anti-lipogenic effect in lactating women's mammary tissue |
[128] |
|
CLA |
Reduce weight gain induced by psychotropic medication |
[129] |
|
CLA |
Favourable effect on serum insulin, but no effect on body composition, energy expenditure of apetite. |
[101] |
|
CLA |
Increased resting metabolic rate, PPAR-γ and hormone-sensitive lipase |
[68] |
|
CLA |
No effect on glucose metabolism or insulin sensitivity on obese population. |
[41] |
|
Trans fatty acids (t-11/t-12, 18:1) |
Gender-based gene expression |
[59] |
|
CLA |
Inhibition on leptin, adiponection - contribute to insulin resistance |
[26] |
|
CLA and Calcium |
Reduces pregnancy-induced hypertension and decreases the intracellular concentration of ionised free calcium in peripheral blood lymphocytes. |
[130] |
|
CLA |
Do not beneficially change risk factors for cardiovascular disease or diabetes |
[94] |
|
CLA and Vaccenic acid |
No effect on blood pressure or arterial elasticity in healthy young men. |
[131] |
|
CLA |
Affect lipid and carbohydrate metabolism and reduced body weight |
[27] |
|
CLA and other PUFA |
Possible role in preventing renal carcinoma |
[132] |
|
CLA |
Reduce colorectal carcinoma |
[133] |
|
CLA |
Enhanced immunological function |
|
|
CLA |
Enhanced C-reactive protein |
[43] |
|
CLA |
Suppresses rheumatoid arthritis |
[109] |
|
CLA |
Lipid peroxidation |
[124] |
|
CLA |
Not good to treat metabolic syndrome |
[134] |
|
CLA |
Not associated with breast cancer |
[76] |
|
10-CLA |
Induces hyperproinsulinaemia, which predicts diabetes and cardiovascular disease |
[124] |
|
CLA |
Ptotective effect on the risk of metastasis in breast cancer |
[75] |
|
10-CLA |
Increases oxidative stress and inflammatroy biomarkers in obese men |
[135] |
|
CLA |
Positive impact on cardioprotective effect. |
[89] |
|
CLA |
Modulation of risk factor associated with atherosclerosis |
[125] |
|
|
||
|
Benjamin and Spener Nutrition & Metabolism 2009 6:36 doi:10.1186/1743-7075-6-36 |
||
