Table 8

Levels of BHB associated with AC-1202, fasting, and dietary regimens

Intervention

Average BHB

levels, mM

Notes

Reference


12 hour fast

0.08 – 0.1

Fasting level on typical diet

This study, [47,48]


AC-1202 (20 grams)

0.36

2 hour post-dose levels

This study


Low carbohydrate diet

0.4 – 0.65

Low carbohydrate diets ranging from 4–10% carbohydrate

[45-48]


Ketogenic diet

0.3 – 1.6

Ketogenic diets given to children with refractive epilepsy

[49,50]


Starvation

4 – 8

5–6 weeks of complete starvation

[51]


Diabetic ketoacidosis

9 – 10

Insulin deficiency and elevated levels of counter-regulatory hormones

[52]


Henderson et al. Nutrition & Metabolism 2009 6:31   doi:10.1186/1743-7075-6-31

Open Data