Table 7

Sarcoplasmic reticulum fatty acid profiles (% of total fatty acids) from rats fed experimental diets for 2 or 6 months.

Duration (months)

2

2

2

6

6

6

Dietary groups

CTL

DHA

ALA

CTL

DHA

ALA

Fatty acids

CI

16:0

9.1 ± 0.36^c

11.2 ± 0.35^a

10.5 ± 0.33^b

9.5 ± 0.46^b

11 ± 0.22^a

10.2 ± 0.05^ab

-

18:0

22.9 ± 0.31

22.5 ± 0.36

22.3 ± 0.26

23.2 ± 0.4

22.6 ± 0.22

22.8 ± 0.12

-

18:1 n-9

4.6 ± 0.18^a

3.7 ± 0.13^b

4.9 ± 0.10^a

4.1 ± 0.13^a **

3.4 ± 0.14^b

4.1 ± 0.1^a **

-

18:1 n-7

2.9 ± 0.06^a

2.3 ± 0.05^c

2.6 ± 0.07^b

2.5 ± 0.08^a ***

2.1 ± 0.07^b ***

2.6 ± 0.05^a

$

18:2 n-6

25.8 ± 0.54^b

20.9 ± 0.76^c

26.9 ± 0.61^a

26.1 ± 0.45^a

23.4 ± 0.36^b *

26.8 ± 0.65^a

-

18:3 n-3

<0.01

<0.01

1.3 ± 0.05

<0.01

<0.01

1.2 ± 0.04**

20:4 n-6

23.3 ± 0.57^a

11.7 ± 0.27^b

14.8 ± 0.41^b

24.4 ± 0.64^a

11.8 ± 0.51^b

15.1 ± 0.58^b

-

20:5 n-3

<0.01

0.9 ± 0.04

1.1 ± 0.28

<0.01

1.0 ± 0.03^b

1.5 ± 0.03^a*

22:4 n-6

1.3 ± 0.03

<0.01

<0.01

1.1 ± 0.04***

<0.01

<0.01

22:5 n-6

3.1 ± 0.23^a

0.8 ± 0.02^a

<0.01

2.8 ± 0.24^b

0.7 ± 0.01^a

<0.01

22:5 n-3

0.7 ± 0.03^b

0.8 ± 0.04^b

3.5 ± 0.13^a

0.6 ± 0.03^b

0.7 ± 0.03^b

3.9 ± 0.06^a *

$

22:6 n-3

4.2 ± 0.16^c

23 ± 0.70^a

8.9 ± 0.46^b

3.2 ± 0.14^c

20.9 ± 0.24^a **

9 ± 0.36^b

$

SFA

32.8 ± 0.41

34.4 ± 0.32

33.8 ± 0.33

33.2 ± 0.84

34.2 ± 0.12

33.6 ± 0.09

-

MUFA

8.2 ± 0.24^a

6.9 ± 0.16^b

8.6 ± 0.28^a

7.8 ± 0.30^a

6.6 ± 0.23^b

8 ± 0.08^a

-

PUFA

59 ± 0.63

58.7 ± 0.38

57.6 ± 0.52

58.9 ± 1.11

59.1 ± 0.26

58.4 ± 0.09

-

n-6 PUFA

54 ± 0.65^a

34 ± 0.79^c

42.7 ± 0.66^b

54.9 ± 1.01^a

36.4 ± 0.43^c *

42.6 ± 0.35^b

-

n-3 PUFA

5 ± 0.17^c

24.8 ± 0.70^a

14.8 ± 0.68^b

4 ± 0.16^c *

22.7 ± 0.24^a *

15.7 ± 0.36^b

$

LA/AA

1.1 ± 0.05^b

1.8 ± 0.08^a

1.8 ± 0.07^a

1.1 ± 0.02^b

2 ± 0.10^a

1.8 ± 0.10^a

-

AA/DHA

5.6 ± 0.20^a

0.5 ± 0.02^c

1.7 ± 0.09^b

7.7 ± 0.26^a ***

0.6 ± 0.03^c

1.7 ± 0.10^b

$

n-6/n-3 ratio

10.9 ± 0.43^a

1.4 ± 0.07^c

2.9 ± 0.18^b

13.9 ± 0.41^a ***

1.6 ± 0.03^c

2.7 ± 0.09^b

$

P/S ratio

1.8 ± 0.04

1.7 ± 0.03

1.7 ± 0.03

1.7 ± 0.07

1.7 ± 0.01

1.7 ± 0.01

-

SFA. MUFA. and PUFA. saturated. monounsaturated. and polyunsaturated FA; CTL. n-3 PUFA free diet; DHA. docosahexaenoic acid-rich diet; ALA. alpha linolenic acid-rich diet.

Data are means ± SEM. n = 6. Dietary effect (CTL versus DHA versus ALA) was compared in rats from the same dietary treatment duration and values with different letters are statistically different. a>b>c. p < 0.01. Time effect (2 months versus 6 months) was compared between rats from the same dietary group. with * = p < 0.05; ** = p < 0.01. *** = p < 0.001). Symbol $ denoted significant cross-interaction. p < 0.05.

Brochot et al. Nutrition & Metabolism 2009 6:14   doi:10.1186/1743-7075-6-14