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Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature

Bryan D Kraft1 and Eric C Westman2*

Author Affiliations

1 Department of Medicine, Duke University Medical Center, DUMC Box # 31179, 2301 Erwin Road, Durham, NC 27710, USA

2 Division of General Medicine, Department of Medicine, Duke University Medical Center, 4020 North Roxboro Street, Durham, NC 27704, USA

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Nutrition & Metabolism 2009, 6:10  doi:10.1186/1743-7075-6-10

Published: 26 February 2009


We report the unexpected resolution of longstanding schizophrenic symptoms after starting a low-carbohydrate, ketogenic diet. After a review of the literature, possible reasons for this include the metabolic consequences from the elimination of gluten from the diet, and the modulation of the disease of schizophrenia at the cellular level.