Table 6 |
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|
Significance levels of gene SNPs associated with % body fat change profiles for carbohydrate-restricted (LC) and fat-restricted (LF) diet treatments. |
||||||||
|
Marker |
P-value |
Coefficient |
FDR |
|||||
|
|
||||||||
|
Area |
SNP |
Gene |
LF |
LC |
LF |
LC |
LF |
LC |
|
|
||||||||
|
Food Intake |
rs1801105 |
HNMT |
0.941 |
0.028 |
-0.03 |
-2.03 |
0.960 |
0.368 |
|
rs12691940 |
HNMT |
0.002 |
0.755 |
0.89 |
-0.12 |
0.041 |
0.974 |
|
|
rs1468271 |
NPY |
0.049 |
0.181 |
-0.89 |
-0.90 |
0.321 |
0.974 |
|
|
Energy Homeostasis |
rs1478290 |
GYS2 |
0.038 |
0.009 |
-0.60 |
-0.86 |
0.321 |
0.209 |
|
rs2838549 |
PFKL |
0.002 |
0.902 |
1.37 |
-0.10 |
0.041 |
0.974 |
|
|
rs3762272 |
PKLR |
0.048 |
0.282 |
-2.24 |
-0.60 |
0.321 |
0.974 |
|
|
rs322695 |
RARB |
0.0001 |
0.012 |
1.29 |
1.03 |
0.005 |
0.209 |
|
|
Adipocyte Regulation |
rs2058112 |
ADIPOR2 |
0.044 |
0.141 |
-0.89 |
-0.78 |
0.321 |
0.974 |
|
rs5950584 |
AGTR2 |
0.507 |
0.0001 |
-0.77 |
-3.31 |
0.732 |
0.021 |
|
|
rs439401 |
APOE |
0.036 |
0.691 |
-0.74 |
-0.15 |
0.321 |
0.974 |
|
|
|
||||||||
|
Abbreviations: Coefficient: linear regression coefficient; FDR: false discovery rate p value, with those in bold type significant at α ≤ 0.05. |
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|
Seip et al. Nutrition & Metabolism 2008 5:4 doi:10.1186/1743-7075-5-4 |
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