Table 2

Studies Which do not Support the Efficacy of HMB Supplementation in Varying Populations

Experiment

Participants

Dosage/Duration

Biochemistry

Performance

Body Composition


Kreider et al. [64]

40 experienced resistance trained M

0, 3, or 6 g/day for 4 weeks

No effect markers of muscle damage

No effect on strength

No effect on LBM or FM

Slater et al. [65]

Experienced resistance trained M

0, 3 g/day for 6 weeks

No effect markers of muscle damage

No effect on strength

No effect on LBM or FM

Paddon-Jones et al. [66], Jennifer et al. [67]

Untrained M

0, or 3 g/day, 6 days prior to a single bout eccentric exercise

NR

No effect on soreness, ROM, or elbow flexor strength

NR

O'Connor and Crowe [20]

Elite M rugby players

P, 3 g/day HMB, or creatine and HMB, during season.

NR

No effect on multistage fitness test or maximal cycle test

NR

Jack et al. [68]

Elite collegiate football players

0, 3 g/day for 4 weeks during football training

NR

No effect on weight lifting strength

No effect on body composition

Jay et al. [69]

26 elite collegiate football players

0, 3 g/day for 4 weeks during 10 day training camp

No effect markers of muscle damage

No effect on performance

No effect on LBM or FM

Kreider et al. [70]

Division 1-A College Football

0, 3 g/day during 4 weeks of resistance training

No effect markers of muscle damage

No effect on strength or sprint performance

No effect on LBM or FM


M = Male; F = Female; LBM = Lean body mass; P = Placebo; FM = Fat mass; NR = Not reported.

Wilson et al. Nutrition & Metabolism 2008 5:1   doi:10.1186/1743-7075-5-1

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