Figure 1.

Possible Mechanisms of HMB action. HMBs proposed mechanisms of action include (A) Increased sarcolemal integrity via conversion to HMG-CoA reductase, (B) enhanced protein synthesis via the mTOR pathway and (C) depression of protein degradation through inhibition of the Ubiquitin pathway.

Wilson et al. Nutrition & Metabolism 2008 5:1   doi:10.1186/1743-7075-5-1
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