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Effect of transilent siRNA PPARα transfection (1.5 μg, overnight) on PPARα expression (relative to β-actin) in islets isolated from UCP2 KO mice and WT mice (compared to the transilent siRNA control vector). Data are expressed as means ± sem (n = 4–7). |
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| Groups |
Control vector |
Transilent PPARα vector |
|
|
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| UCP2 KO |
0.349 ± 0.136 |
0.029 ± 0.02 |
| WT |
0.242 ± 0.116 |
0.024 ± 0.007 |
Fatehi-Hassanabad and Chan Nutrition & Metabolism 2007 4:6 doi:10.1186/1743-7075-4-6 |
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