Table 4 |
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|
Lipid characteristics of high fat diets used to induce steatosis and steatohepatitis |
||||||||
|
coconut diet |
butter diet |
Lieber |
Zou |
Rivera |
Gauthier |
Fan |
||
|
|
||||||||
|
Rat |
Wistar |
Wistar |
Sprague Dawley |
Sprague Dawley |
Wistar |
Sprague Dawley |
Sprague Dawley |
|
|
Fat (w/w) |
45% coconut |
45% butter |
30.1% corn oil 17.6% olive oil 1.7% safflower oil |
35.7% corn oil |
15% corn oil |
3.4% corn oil 14.6% lard |
10% lard oil 2% cholesterol |
|
|
SFA (% fat) |
86.5 |
51.3 |
13 |
13 |
13 |
34 |
39 |
|
|
MUFA (% fat) |
5.8 |
21 |
41 |
24 |
27.6 |
42 |
45 |
|
|
PUFA (% fat) |
1.8 |
3 |
42 |
59 |
54.7 |
20 |
21 |
|
|
Carbohydrate (w/w) |
24.7% corn starch |
16.2% dextrin maltose |
13.4% sucrose |
50% sucrose |
39% corn starch |
nd |
||
|
Time of diet (week) |
14 |
14 |
3 |
6 |
6 |
8 |
16 |
12 |
|
steatosis |
no |
no |
mild |
mild |
no |
yes |
yes |
yes |
|
inflammation |
no |
no |
yes |
yes |
no |
nd |
nd |
mild |
|
fibrosis |
no |
no |
yes |
nd |
no |
nd |
nd |
no |
|
|
||||||||
|
Abbreviations: SFA, saturated fatty acid; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated fatty acid; nd, not determined. |
||||||||
|
Romestaing et al. Nutrition & Metabolism 2007 4:4 doi:10.1186/1743-7075-4-4 |
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