Nutrition & Metabolism

official impact factor 2.35

Open Access Letters to the Editor

Letter to the editor: healthy alternatives to trans fats

Frédéric Destaillats*, Julie Moulin and Jean-Baptiste Bezelgues

Author Affiliations

Nestlé Research Center, Lausanne, Switzerland

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Nutrition & Metabolism 2007, 4:10 doi:10.1186/1743-7075-4-10

Published: 27 April 2007

Abstract

Consumption of trans fats is associated with an increase of cardiovascular disease (CVD) risk. To comply with regulatory policies and public health authorities recommendations, trans fats should be replaced in food products. The study by Sundram et al. (Nutrition & Metabolism 2007, 4:3) reporting the effect on CVD risk factors of interesterified fat (IE) and partially hydrogenated soybean oil (PHSO) compared to palm olein (POL) has been critically analyzed. The study design and in particular the composition of the tested fats was not suitable to properly answer the question raised regarding the effect of alternative ingredients to trans fats on plasma lipids. The observed effects are divergent with predicted data derived from the literature model consolidated using the individual results of 60 randomized clinical trials. The results of the study published by Sundram and co-workers have to be considered with awareness.