|
Mean blood pressure change (± SEM) from baseline after exercise andnon-exercise control by AT1R A/C genotype group over 10 h (95% confidence interval). |
||||||
| Dietary |
Calcium |
Intake |
Level |
|||
|
|
||||||
| Low |
High |
|||||
|
|
||||||
| Non-Exercise Control |
40% VO2max |
60% VO2max |
Non-Exercise Control |
40% VO2max |
60% VO2max |
|
|
|
||||||
| (n = 16) |
AT1R |
AA |
(n = 11) |
|||
|
|
||||||
| SBP |
11.0 ± 2.2 (6.6,15.4) |
5.8 ± 2.1 (1.5,10.1) |
3.5 ± 2.3† (-1.2,8.1) |
13.8 ± 2.6 (8.5,19.1) |
10.4 ± 2.6 (5.2,15.6) |
6.9 ± 2.8* (1.2,12.5) |
| DBP |
-1.9 ± 1.6 (-5.1,1.3) |
-3.8 ± 1.4 (-6.6,-1.0) |
-3.5 ± 1.4 (-6.4,-0.7) |
0.9 ± 1.9 (-2.9,4.7) |
-3.4 ± 1.7 (-6.8,0.0) |
-3.1 ± 1.7 (-6.5,0.3) |
|
|
||||||
| (n = 9) |
AT1R |
CC/AC |
(n = 12) |
|||
|
|
||||||
| SBP |
12.6 ± 2.9 (6.7,18.5) |
5.1 ± 2.8* (-0.6,10.8) |
10.5 ± 3.1 (4.2,16.7) |
6.0 ± 2.5 (0.9,11.1) |
11.8 ± 2.4 (6.8,16.7) |
4.8 ± 2.7 (-0.6,10.2) |
| DBP |
-1.2 ± 2.1 (-5.4,3.1) |
-4.3 ± 1.9 (-8.0,-0.6) |
-1.3 ± 1.9 (-5.0,2.5) |
-5.2 ± 1.8 (-8.9,-1.5) |
-0.6 ± 1.6 (-3.8,2.6) |
-5.3 ± 1.6 (-8.6,-2.0) |
|
AT1R A/C = angiotensin II type 1 receptor polymorphism; Low = < median dietary calcium intake; High = ≥ median dietary calcium intake; VO2max = maximal oxygen consumption; SBP = systolic blood pressure; DBP = diastolic blood pressure. *p < 0.05, † p < 0.01 exercise vs non-exercise control | ||||||
Pescatello et al. Nutrition & Metabolism 2007 4:1 doi:10.1186/1743-7075-4-1 |
||||||