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Demographic and clinical measures in cases and controls. For cases and controls categorical variables are presented as percentage of patients; chi-square test was used for group differences; and continuous variables are presented as mean values (standard deviation) or *median values (25/75th interquartiles) because of skewed distribution. The p values were obtained by *Mann-Whitney test. #: data for 913 patients for ejection fraction, data for 200 controls/1026 patients for apoA-I and apoB, for 200 controls/905 patients for Hs-CRP, and for 200 controls/1060 patients for Lp(a). |
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| Variable |
Cases n = 1102 |
Controls n = 444 |
P- value |
|
|
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| Age, years |
61.1 (10.1) |
59.7 (7.4) |
<0.001 |
| BMI, kg/m2 |
27.2 (3.7) |
26.7 (4.3) |
0.02 |
| Sex, male % |
74.7 |
72.7 |
0.43 |
| Current smoking, % |
27.3 |
11.0 |
< 0.001 |
| Diabetes mellitus, % |
21.6 |
3.7 |
<0.001 |
| Hypertension, % |
71.9 |
28.6 |
<0.001 |
| Family history of CAD, % |
38.2 |
20.1 |
<0.001 |
| Statins, % |
35.8 |
6.3 |
< 0.001 |
| ACE inhibitors, % |
47.8 |
8.3 |
<0.001 |
| Angiotensin receptor blockers, % |
5.0 |
3.8 |
0.327 |
| Ejection fraction <40%#, % |
7.6 |
- |
- |
| Hs-CRP*, mg/l# |
4.4 (1.9/12.4) |
1.5 (0.9/3.8) |
<0.001 |
| PLTP, U/l |
25.5 (9.8) |
22.4 (7.4) |
<0.001 |
| CETP, U/l |
49.9 (20.9) |
41.4 (17.4) |
<0.001 |
| Total cholesterol, mg/dl |
219.7 (45.7) |
238.4 (41.8) |
<0.001 |
| LDL cholesterol, mg/dl |
141.0 (40.1) |
155.5 (35.1) |
<0.001 |
| HDL cholesterol, mg/dl |
48.8 (14.7) |
59.4 (15.9) |
<0.001 |
| Triglyceride*, mg/dl |
141 (102/193) |
120 (87/167) |
<0.001 |
| Apolipoprotein A-I, g/l# |
1.31 (0.24) |
1.62 (0.28) |
<0.001 |
| Apolipoprotein B, g/l# |
1.20 (0.28) |
1.19 (0.23) |
0.3 |
| Lipoprotein(a), mg/dl# |
36.3 (38.9) |
24.2 (30.4) |
<0.001 |
Schlitt et al. Nutrition & Metabolism 2006 3:5 doi:10.1186/1743-7075-3-5 |
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