Brief communication
Short-term arginine deprivation results in large-scale modulation of hepatic gene expression in both normal and tumor cells: microarray bioinformatic analysis
-
* Corresponding author: Nancy L Thompson Nancy_Thompson@brown.edu
1 Division of Hematology and Oncology, Dept. of Medicine, Rhode Island Hospital – Brown Medical School, Providence, RI, USA
2 COBRE Center for Genetics and Genomics, Division of Biology and Medicine, Brown University, Providence, RI, USA
3 Dept. Pathology and Laboratory Medicine, Rhode Island Hospital – Brown Medical School, Providence, RI, USA
Nutrition & Metabolism 2006, 3:37 doi:10.1186/1743-7075-3-37
Published: 8 September 2006Additional files
Additional file 1:
Major functional classes of arginine-sensitive genes in normal hepatic cells. GeneSpring functional categories of arginine-responsive genes in normal hepatic cells based on 9-way comparison of three independent data sets. Numbers of genes in each class and subclass are shown in parentheses along with gene accession numbers. Increase (I) and Decrease (D) defined as a two fold or higher change in expression from + arg to - arg.
Format: XLS Size: 27KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 2:
Major functional classes of arginine-sensitive genes in hepatic tumor cells. GeneSpring functional categories of arginine-responsive genes in tumorigenic hepatic cells based on 9-way comparison of three independent data sets. Numbers of genes in each class and subclass are shown in parentheses along with gene accession numbers. Increase (I) and Decrease (D) defined as a two fold or higher change in expression from + arg to - arg.
Format: XLS Size: 61KB Download file
This file can be viewed with: Microsoft Excel Viewer