Effect of AICAR on adipocyte protein marker expression in DIO treated mice after 6 weeks of treatment. Total protein epididymal fat content from 6 weeks AICAR treated STD and DIO treated mice was isolated. The expression for various key adipogenic transcription factors including C/EBPα, C/EBPβ, PPARγ and SREBP1 was examined by immunoblot analysis as described in Materials and Methods.
Giri et al. Nutrition & Metabolism 2006 3:31 doi:10.1186/1743-7075-3-31