Figure 2.

The effects of octanoate on expression of selected lipogenic genes and the antagonizing effects of troglitazone. Cells were incubated with octanoate (1 mM) for 24 h with or without troglitazone (5 μM), using DMSO as the vehicle. (Upper panel) The expression of CD36, diacylglycerol acyltransferase 2 (DGAT2), fatty acid synthase (FAS), and lipoprotein lipase (LPL) were analyzed by RT-qPCR using house keeping gene HPRT as the endogenous reference. The results were normalized to control cells. Results are mean +/- SE, n = 3, *p < 0.05.