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Effect of 12 wk α-tocopherol supplementation (E+) or restriction (E-) on α-tocopherol concentrations in plasma and tissue of rats1,2,3 |
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| Tissue |
E+ (100 mg all-rac-α-tocopherol) |
Control (30 mg all-rac-α-tocopherol) |
E- (<10 mg total tocopherol) |
| n = 10 |
n = 13 |
n = 10 |
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| Plasma (μmol/L) |
36 ± 6.0 |
20 ± 1.2 |
< 1.0 |
| Liver (nmol/g protein) |
2.08 ± 0.08 |
0.68 ± 0.04 |
0.007 ± 0.0005 |
| Kidney (nmol/g protein) |
1.97 ± 0.51 |
1.41 + 0.55 |
ND4 |
| Brain (nmol/g protein) |
1.90 ± 1.19 |
1.29 ± 0.29 |
0.59 ± 0.19 |
| Testis (nmol/g protein) |
1.19 ± 0.06 |
1.00 ± 0.06 |
0.026 ± 0.002 |
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1All 3 diets contained 460 μg phylloquinone/kg of diet 2Plasma and tissue α-tocopherol in the E+ group are higher than those in the Control and E- groups (P ≤ 0.05) 3Values are mean ± SEM 4Not detectable | |||
Tovar et al. Nutrition & Metabolism 2006 3:29 doi:10.1186/1743-7075-3-29 |
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