Table 1

Effect of diet on weight, BMI, HbA1c and fasting lipids. Sixteen obese patients with type 2 diabetes started at month 0 on a diet with the proportions: 20 % carbohydrates, 30 % protein and 50 % fat. The figures shown are before, 3, 6 and 22 months after the dietary change

Months

0

3

P*

6

P*

22

P*

Weight (kg)

100.6 ± 14.7

91.9 ± 14.7

<0.001

89.2 ± 14.3

<0.001

92.0 ± 14.0

<0.001

BMI (kg/m²)

36.1 ± 4.2

33.0 ± 4.5

<0.001

32.0 ± 4.3

<0.001

32.9 ± 3.5

<0.001

HbA1c (%)

8.0 ± 1.5

5.9 ± 0.7

<0.001

6.6 ± 1.0

<0.001

6.9 ± 1.1

<0.001

Lipids(mmol/l)

Tot-Chol.

5.6 ± 1.2

5.8 ± 1.1

0.4

6.1 ± 1.1

0.06

5.7 ± 1.2

0.9

HDL-Chol.

1.1 ± 0.2

1.2 ± 0.2

<0.002

1.3 ± 0.2

<0.001

1.3 ± 0.3

<0.001

§ Triglycerides

1.4(1;1,8)

1.2(0.8;1,4

0.01

1.4(0.9;1.7)

0.4

1.4(1.2;1.9)

0.9

Chol/HDL

5.4 ± 1.5

5.0 ± 1.5

0.02

5.0 ± 1.7

0.07

4.6 ± 1.6

<0.001

§ TG/HDL

1.4(0.9;1.7)

1.0(0.6;1.2)

0.003

1.0(0.7;1.5)

0.03

1.3(0.8;1.5)

0.2

§ given as median with 25 and 75 percentiles. * p values are for differences from baseline.

Nielsen and Joensson Nutrition & Metabolism 2006 3:22   doi:10.1186/1743-7075-3-22