Table 4

Results of the association test of each SNP against the phenotypic variation residual from the regression of covariates in Table 3. Results significant at alpha ≤ 0.05 are indicated in bold. Also shown are the FDR corrected p-value, the degrees of freedom in the regression model, the regression coefficient indicating the size of the effect of the minor allele, and the minimum effect size for 80% power of detection, relative to the standard deviation.

SNP
Gene
p-value
FDR
degf
coeff
power
SNP type

rs936960
LIPC
0.7354
0.8011
47
0.351
2.08
intron 1
rs417344
LIPC
0.1322
0.5433
48
1.175
1.57
~5.5 kb upstream from LIPC
rs6083
LIPC
0.6944
0.8011
37
-0.226
1.25
S215N
rs295
LPL
0.5519
0.7843
44
-0.526
1.49
intron 6
rs328
LPL
0.1973
0.5744
51
-1.330
1.76
exon 9, *474S
rs10422283
LIPE
0.1610
0.5433
41
0.916
1.24
intron 1
rs1556478
LIPA
0.7417
0.8011
33
0.228
1.29
intron 5
rs6586179
LIPA
0.2575
0.6321
43
-1.189
2.08
exon 1, R23G
rs4245232
LIPG
0.1561
0.5433
43
0.906
1.50
~1.5 kb upstream
rs814628
LIPF
0.0002
0.0059
43
-3.658
1.86
exon 4, Ala161>Thr
rs2287754
GYS1
0.6950
0.8011
33
-0.324
1.51
5' UTR
rs1478290
GYS2
0.4504
0.7843
57
-0.381
1.13
~3.5 Kb upstream
rs1871143
GYS2
0.5236
0.7843
38
-0.381
1.31
intron 11
rs2306179
GYS2
0.0068
0.0610
42
-1.717
1.40
intron 5
rs4688046
GSK3B
0.5148
0.7843
42
-0.382
1.37
intron 3
rs334555
GSK3B
0.4553
0.7843
41
0.925
2.09
intron 1
rs711752
CETP
0.2127
0.5744
44
0.677
1.13
intron 1
rs3764261
CETP
0.6900
0.8011
39
0.263
1.36
~2.6 kb upstream
rs5880
CETP
0.0782
0.4220
42
2.769
2.71
P390A
rs1532624
CETP
0.5299
0.7843
49
0.339
1.12
intron 7
rs5883
CETP
0.0018
0.0237
54
-2.854
1.94
exon 9, synonymous
rs5070
APOA1
0.4406
0.7843
39
-0.454
1.41
Intron
rs4520
APOC3
0.4275
0.7843
36
-0.497
1.32
G34G
rs2071521
APOC3
0.9176
0.9176
43
-0.053
1.13
Upstream
rs694066
GAL
0.0231
0.1557
54
2.105
2.22
intron 1
rs1468271
NPY
0.7401
0.8011
46
-0.378
2.43
intron 1
rs26312
GHRL
0.7832
0.8133
61
0.233
1.50
~1 kb upstream

Ruaño et al. Nutrition & Metabolism 2006 3:20   doi:10.1186/1743-7075-3-20