|
Clinical and laboratory data in subject groups |
||||
| Parameter |
CTL |
HYPER |
HYPO |
ANOVA |
|
|
||||
| N |
30 |
46 |
23 |
|
| Gender (M/F) |
10/20 |
13/33 |
5/18 |
ns |
| Age (years) |
41.7 ± 2.0 |
34.9 ± 1.6* |
39.4 ± 2.5 |
0.029 |
| BMI (kg/m2) |
22.0 ± 0.4 |
21.2 ± 0.4††† |
24.2 ± 0.61* |
0.0003 |
| Glucose (mmol/L) |
4.88 ± 0.11 |
5.47 ± 0.07*** |
5.08 ± 0.12† |
<0.0001 |
| Insulin (pmol/L) |
34.0 ± 5.5 |
60.8 ± 4.9*** |
33.8 ± 2.8†† |
<0.0001 |
| HOMA-IR |
1.10 ± 0.20 |
1.86 ± 0.16** |
1.02 ± 0.11†† |
0.0004 |
| FT4 (pmol/L) |
17.4 ± 0.4 |
64.5 ± 8.4*** |
9.1 ± 0.6*††† |
<0.0001 |
| FT3 (pmol/L) |
5.7 ± 0.1 |
13.3 ± 1.2*** |
3.2 ± 0.2**††† |
<0.0001 |
| TSH (mU/L) |
2.1 ± 0.1 |
0.03 ± 0.02*** |
69.5 ± 21.1**††† |
<0.0001 |
|
Results are expressed as average ± SEM for the groups indicated as control (CTL), hyperthyroid (HYPER) and hypothyroid (HYPO) where N = number of subjects per group. Significance was calculated by ANOVA with Bonferroni post-hoc test. Differences vs. control (CTL) group are indicated as *P < 0.05,**P < 0.01,***P < 0.001; and differences for hyperthyroid vs. hypothyroid as †p < 0.05, ††p < 0.01, †††p < 0.001, ns = not significant. | ||||
Yu et al. Nutrition & Metabolism 2006 3:13 doi:10.1186/1743-7075-3-13 |
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