Table 1

Rates of hepatic glycogen changes and ATP changes (nmol·min-1·g-1 of liver ww).

Experimental conditions

Control (KHB)
Group A,
n = 7
 G 6 mM
Group B,
n = 8
 G 30 mM
Group C,
n = 8
 Insulin
Group D,
n = 5
 Insulin + G 6 mM
Group E,
n = 5
 Insulin + G 30 mM
Group F,
n = 5
GLYCOGEN
 -387 ± 73
 (a) -64 ± 109*
p = 0.02 vs control
(b) -474 ± 102
NS vs control
 (a) +52 ± 95**
p = 0.003 vs control
(b) -277 ± 80
NS vs control
 -431 ± 29
NS vs control
 -29 ± 73
p < 0.003 vs insulin NS vs G6(a)
 +139 ± 47
p < 0.00001 vs insulin
p = 0.015 vs G30(a)
ATP
 -7.28 ± 0.76
 -10.14 ± 1.61
NS vs control
 -5.98 ± 1.22
NS vs control
 -8.06 ± 1.22
NS vs control
 -3.38 ± 0.17
p = 0.03 vs insulin
p = 0.01 vs G6
 -0.10 ± 0.42
p = 0.003 vs insulin
p = 0.006 vs G30

100% glycogen = 73 ± 8.5 μmol glycosyl units·g-1 of liver ww; 100% ATP = 2.60 ± 0.65 μmol·g-1 of liver ww. The rates of glycogen changes were biphasic in group B and C; the first phase (a) lasted *20 min or **60 min. Mean ± SEM.

Baillet-Blanco et al. Nutrition & Metabolism 2005 2:32   doi:10.1186/1743-7075-2-32