|
Percent Difference in Immunocytochemical Staining for RANKL and OPG |
||||
| 50% NR |
||||
|
|
||||
| Osteoclast |
Osteoblast |
|||
|
|
||||
| RANKL |
OPG |
RANKL |
OPG |
|
|
|
||||
| 3 Month 50% vs Control |
+250 |
-152 |
+320 |
-20 |
| 6 Month 50% vs Control |
+240 |
0 |
+700 |
-100 |
|
As shown in Table 4, the percent relative difference in immunocytochemical staining in rats on a diet containing 50% NR Mg for RANKL was increased at 3 and 6 months in osteoclasts and in osteoblasts. Staining for OPG was decreased in both cell lines three of the four time points compared to control. | ||||
Rude et al. Nutrition & Metabolism 2005 2:24 doi:10.1186/1743-7075-2-24 |
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