|
Percent Difference in Immunocytochemical Staining for RANKL and OPG |
||||
| 25% NR |
||||
|
|
||||
| Osteoclast |
Osteoblast |
|||
|
|
||||
| RANKL |
OPG |
RANKL |
OPG |
|
|
|
||||
| 2 Month 25% vs Control |
86 |
-150 |
-10 |
-113 |
| 4 Month 25% vs Control |
-16 |
-160 |
-232 |
-160 |
| 6 Month 25% vs Control |
116 |
-700 |
-82 |
-700 |
|
As shown in Table 2, the percent relative difference in immunocytochemical staining in rats on a diet containing 25% NR Mg for RANKL in osteoclasts was increased at 2 and 6 months and decreased in osteoblasts. Staining for OPG was markedly decreased in both cell lines at all time points compared to control. | ||||
Rude et al. Nutrition & Metabolism 2005 2:24 doi:10.1186/1743-7075-2-24 |
||||