Table 9

Liver enzyme activities
Diet CPT1 activity CPT1 activity ACOX activity FAS activity
nmol/mg/min - 15μM Malonyl-CoA nmol/mg/min + 15μM Malonyl-CoA nmol/mg/min nmol/mg/min
High fat 2.35 (1.83–3.74) 1.24 (1.05–4.41) 16.8 (14.4–30.6) 0.31 (0.24–0.38)
FO 3.42 (2.22–3.73) 2.10 (1.61–2.20) 43.8 (33.3–54.7)a** 0.57 (0.36–0.63)c***
KO 2.50 (1.84–3.08) 1.49 (1.28–2.15) 22.4 (16.8–39.4) 0.20 (0.12–0.22)
p (K-W) 0.337 0.120 0.005 0.001

Acyl-CoA oxidase (ACOX), fatty acid synthase (FAS) and carnitine palmitoyltransferase 1 (CPT1) activities were measured as described in Materials and Methods. CPT1 activity was measured with and without the addition of 15 μM malonyl-CoA. Data shown as median and range. High fat (n = 6), FO (n = 5) and KO (n = 6). a = HF vs FO, c = FO vs KO. **= p <0.01 and ***= p <0.001. K-W, p indicates the p -value with the Kruskal-Wallace test. FO; fish oil, KO; Krill oil.

Tillander et al.

Tillander et al. Nutrition & Metabolism 2014 11:20   doi:10.1186/1743-7075-11-20

Open Data