Table 2

Serum clinical safety markers between groups following the feeding intervention
Variable CTL (n = 6) WD (n = 8) WD + AF (n = 8) ANOVA p-value
Metabolic markers
Glucose (mg/dl) 143 ± 11a 205 ± 13b 204 ± 13b 0.005
Cholesterol (mg/dl) 74.7 ± 2.7 80.8 ± 2.0 77.8 ± 2.2 0.21
Triglycerides (mg/dl) 73.3 ± 4.9 123.1 ± 21.0 131.4 ± 18.5 0.088
Markers of liver health and function
Total Protein (g/dl) 7.2 ± 0.1 7.1 ± 0.1 7.2 ± 0.2 0.81
Albumin (g/dl) 3.47 ± 0.03 3.36 ± 0.03 3.39 ± 0.04 0.18
Total bilirubin (mg/dl) 0.10 ± 0.00 0.10 ± 0.00 0.10 ± 0.00 1.00
Alkaline Phosphatase (U/L) 133 ± 12a 93 ± 9b 89 ± 7b 0.006
Alanine aminotransferase (U/L) 60.5 ± 11.3 75.3 ± 15.6 60.9 ± 7.6 0.62
Gamma-glutamyltransferase (U/L) < 3 < 3 < 3 N/A
Globulin (g/dl) 3.70 ± 0.03 3.74 ± 0.03 3.78 ± 0.08 0.67
Other serum markers
Sodium (mEq/L) 150 ± 3 147 ± 1 147 ± 1 0.29
Potassium (mEq/L) 5.57 ± 0.21 5.60 ± 0.27 5.09 ± 0.12 0.17
Chloride (mEq/L) 98.6 ± 1.5 99.6 ± 0.5 99.5 ± 0.4 0.19
Total CO2 (mEq/L) 42.8 ± 1.0 40.9 ± 0.8 40.5 ± 0.8 0.18
Calcium (g/dl) 11.1 ± 0.1a 11.4 ± 0.1b 11.2 ± 0.1a,b 0.043
Phosphorus (mg/dl) 6.12 ± 0.12 6.63 ± 0.19 6.21 ± 0.06 0.038
Blood urea nitrogen (mg/dl) 16.0 ± 0.6 14.4 ± 0.5 14.3 ± 0.6 0.082
Creatinine (mg/dl) 0.49 ± 0.01a 0.45 ± 0.01a,b 0.44 ± 0.01b 0.016
Creatine Kinase (U/L) 64.3 ± 5.4 69.8 ± 8.2 79.4 ± 7.2 0.37

Notes: Tukey post-hoc comparisons performed when ANOVA p < 0.05; different letter superscripts indicate significant differences between groups.

"Legend: Bold-faced values are significant between-treatment differences when Tukey post-hoc comparisons performed (p < 0.05); different letter superscripts indicate significant differences between groups."

Mobley et al.

Mobley et al. Nutrition & Metabolism 2014 11:19   doi:10.1186/1743-7075-11-19

Open Data