Effects of CTL, WD, and WD + AF feeding on SOD2 mRNA (A), SOD2 mRNA (B), Tnf-α mRNA (C), p47phox mRNA (D), p67phox mRNA (E), and IL-6 mRNA (F). WD + AF rats experienced a decrease in liver Tnf-α mRNA expression (C) compared to WD and CTL rats; WD + AF rats tended to increase liver SOD2 mRNA (A) and Il-6 mRNA compared to CTL (F) rats; WD + AF rats tended to increase liver p47phox mRNA compared to WD (C) rats. Abbreviations and symbols: CTL = control low-fat/low-sugar 14% diet, WD = Western diet, WD + AF = Western diet + anti-inflammatory supplement; In C, different superscript letters represents differences between groups (a > b, p < 0.05).
Mobley et al. Nutrition & Metabolism 2014 11:19 doi:10.1186/1743-7075-11-19