Kochujang, fermented soybean-based red pepper paste, decreases visceral fat and improves blood lipid profiles in overweight adults
1 Department of Food Science and Human Nutrition, Chonbuk National University, Obesity Research Center, 664-14 Dukjin-Dong 1-Ga, Jeonju, Jeonbuk, 561-756, Republic of Korea
2 Clinical Trial Center for Functional Foods, Chonbuk National University Hospital, 634-18, Geumam-dong, Deokjin-gu, Jeonju, Jeonbuk, 561-172, Republic of Korea
3 Department of Pharmacology, Chonbuk National University, Medical School, Jeonju, Jeonbuk, 561-172, Republic of Korea
4 Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, 48824-1224, USA
Nutrition & Metabolism 2013, 10:24 doi:10.1186/1743-7075-10-24Published: 26 February 2013
Health benefits of Kochujang (KCJ) and its bioactive compounds have been reported in several in vitro and animal studies.
The aim of this study was to investigate the efficacy of KCJ supplementation on body composition and blood lipid profiles in overweight adults.
Sixty overweight men and women with BMI ≥23 kg/m2 and waist-hip-ratio (WHR) ≥0.90 for men and ≥0.85 for women were randomly assigned to a KCJ supplement (n=30, 32 g/day) or placebo (n=30, 32 g/day) group for a 12-week, double-blind, placebo controlled study. We measured anthropometric parameters, serum lipid profiles, abdominal fat distribution by computerized tomography and calculated the atherosclerosis indices in 53 subjects (n=26 in KCJ group, n=27 in placebo group) who completed the study.
After 12 weeks, the KCJ group showed a significant reduction in visceral fat (cm2) (p<0.05), although body weight (kg) and WHR did not change. Serum concentration of triglycerides and ApoB were decreased when compared to those of the placebo group.
KCJ supplementation (32 g/day) for 12 weeks in overweight adults showed anti-atherosclerotic and anti-obesogenic effects.
Clinical trials.gov Identifier: NCT01532375