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Body weight, tissues and fasting plasma metabolites |
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| REF |
CAF |
CAF-ZD |
|
|
|
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| Final body weight (g) |
443.78 ± 21.42 |
540.20 ± 16.69 * |
477.82 ± 12.09 + |
| Retroperitoneal (g) |
3.73 ± 0.44 |
10.65 ± 0.48 ** |
5.78 ± 0.23 + |
| Epididymal (g) |
4.65 ± 0.41 |
10.73 ± 0.43 ** |
5.96 ± 0.30 + |
| Gastrocnemius (g) |
2.69 ± 0.13 |
2.78 ± 0.01 |
2.79 ± 0.03 |
| Heart (g) |
1.25 ± 0.07 |
1.48 ± 0.01 |
1.46 ± 0.02 |
| Liver (g) |
13.53 ± 0.79 |
16.69 ± 0.15 |
15.47 ± 0.12 |
| Glucose (mmol/l) |
12.80 ± 1.51 |
12.10 ± 1.02 |
14.78 ± 1.11 |
| Insulin (μU/ml) |
19.75 ± 2.05 |
98.04 ± 16.01 ** |
43.27 ± 8.26 + |
| Fatty acid (mmol/l) |
0.47 ± 0.22 |
0.42 ± 0.68 |
0.30 ± 0.39 ** |
| Triacylglycerol (mmol/l) |
2.27 ± 0.30 |
4.59 ± 0.58 ** |
4.11 ± 0.95 |
|
Data are the mean ± SEM. Values significantly different from those obtained in the group of rats fed a chow diet (REF) are indicated by * (p < 0.05) and ** (p < 0.01). Data measured in the group of rats treated with ZD7114 (CAF-ZD) and significantly different from those in the group of rats fed a cafeteria diet (CAF) are shown by + (p < 0.05). | |||
Darimont et al. Nutrition & Metabolism 2004 1:4 doi:10.1186/1743-7075-1-4 |
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